The imidazoline receptor in control of blood pressure by clonidine and allied drugs.
نویسندگان
چکیده
Clonidine, moxonidine, and rilmenidine are centrally acting antihypertensive agents that lower arterial pressure by inhibiting the tonic activity of sympathoexcitatory neurons in the rostral ventrolateral medulla. Competing hypotheses have been put forward by different investigators to explain the sympathoinhibition evoked by "imidazoline drugs": either via central actions at α2-adrenergic receptors or novel I1-imidazoline receptors. These different perspectives are presented in the accompanying reviews.
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ورودعنوان ژورنال:
- The American journal of physiology
دوره 273 5 Pt 2 شماره
صفحات -
تاریخ انتشار 1997